STUDY DESIGN LIMITATIONS The authors report a retrospective, uncontrolled, multicenter series of 53 patients, with attrition to 42 patients after only 6 months. The absence of a control group or blinding means that natural variability, regression to the mean, or periods of spontaneous stability cannot be excluded as explanations for their findings. The authors acknowledge that “the absence of a control group and blinding, as well as the relatively small number of individuals followed, can be mentioned”. Furthermore, the inclusion […]