ABSTRACT Objective: To evaluate changes in corneal sensitivity and ocular surface in leprosy patients from a university hospital in Northern Brazil. Methods: A case-control study was conducted with 16 leprosy patients (32 eyes) and 20 healthy controls (40 eyes). All participants underwent a single assessment that included ocular surface staining, tear film break-up time test, Schirmer I test, and corneal sensitivity testing using a Semmes-Weinstein aesthesiometer. Results: Most leprosy patients were male (68.8%), whereas the sex distribution was balanced in […]

ABSTRACT Objective: To describe the clinical features and multidisciplinary management of paralytic lagophthalmos secondary to peripheral facial palsy, focusing on ocular complications. Methods: A cross-sectional, observational, and retrospective analysis was conducted on five patients treated at an ophthalmologic emergency service in Curitiba, Brazil. Results: All patients developed keratitis associated with lagophthalmos, confirming the correlation between these conditions. Treatment included ocular lubrication and corneal reepithelialization, but nocturnal eye occlusion was prescribed in only some cases. Referrals varied with symptom duration: acute […]

ABSTRACT Thygeson’s keratitis is a chronic bilateral inflammation of the cornea, characterized by recurrent intraepithelial opacities, intense photophobia, and visual fluctuations, especially in children. Topical corticosteroids are effective, but their prolonged use carries risks and frequent recurrences. We report the case of an 11-year-old girl with refractory Thygeson’s keratitis treated with topical tacrolimus 0.03%. After an initial response to corticosteroids, an early recurrence occurred within 15 days. With the introduction of tacrolimus, there was complete resolution of signs and symptoms, […]

Anterior segment-optical coherence tomography (AS-OCT) imaging provide a range of characteristic patterns that could be used as an additional tool in the diagnosis and management of infectious keratitis.(,) We describe the AS-OCT findings of a patient with fungal keratitis. A 65-year-old man with a history of vegetal trauma to his left eye, presented to the emergency room complaining of pain and blurred vision in the right for three weeks. The best corrected visual acuity was 3/10 in the left eye. […]

Measles is a contagious disease caused by morbillivirus, a virus of the family paramyxoviridae.() It evolves through four phases: incubation, invasion, eruption and desquamation. Ophthalmologic manifestations are rare. They may occur during the invasive and eruptive phases.() Measles keratitis is the most concerning manifestation; it may vary from simple superficial punctate keratitis to corneal perforation. We report a case of acute keratitis occurring during the eruptive phase of measles in an unvaccinated adult during an epidemic. […]

CASE REPORT […]

ABSTRACT To describe a case of treatment-resistant corneal infiltrate in a patient 4 months after penetrating keratoplasty. The etiological diagnosis was established through microbiology and in vivo corneal confocal microscopy. A 80-year-old female patient presented with stromal infiltrate in the donor corneal bud 4 months following penetrating keratoplasty. Initially, the corneal culture was positive for Candida parapsilosis. In vivo corneal confocal microscopy demonstrated approximately 4 μm hyperreflective spherical microorganisms with a suggestive Candida spp. A second corneal culture was positive […]

ABSTRACT Objective: To evaluate patients’ clinical-epidemiological profile and causative agents of infectious keratitis on patients submitted to culture obtained from corneal smears in an ophthalmological emergency in a reference hospital. Methods: Retrospective analysis of medical records and corneal culture examination results. The data were collected after the approval of the Human Research Ethics Committee. Results: Most patients were male, with an average age of 47.6 years old, Caucasian ethnicity, low level of education, and from the Greater Florianópolis area. Ocular […]