ABSTRACT Normal-tension glaucoma (NTG) is a glaucomatous optic neuropathy that occurs in the absence of intraocular hypertension, and its pathophysiology is not solely dependent on pressure-related factors. Extrinsic mechanisms, such as autonomic dysfunction and microvascular hemodynamic alterations, have been implicated in its progression, with obstructive sleep apnea (OSA) standing out as an important contributing factor. We report the case of a patient with NTG and severe OSA confirmed by polysomnography, who exhibited progressive structural and functional loss despite controlled intraocular […]

ABSTRACT Objective: To characterize structural optic nerve changes in Ecuadorian glaucoma patients using optical coherence tomography data from 2015 to 2022. Methods: This retrospective study analyzed anonymized optical coherence tomography data from 301 eyes of 162 patients diagnosed with primary open-angle glaucoma. Data were acquired using the Nidek RS-330 and analyzed with Statistical Package for the Social Sciences, version 21. We assessed peripapillary retinal nerve fiber layer thickness (global, quadrants, and clock-hour sectors) and cup-to-disc ratios. Results: The mean global […]

ABSTRACT Objective: To analyze the epidemiological and economic aspects of hospital admissions for glaucoma in Brazil between 2018-2024. Methods: Analytical ecological time-series study using SIH (Hospital System Information)/SUS data from the DATASUS platform. All hospital admissions with a diagnosis of glaucoma during the period were included. Results: A total of 50,062 admissions were recorded, reflecting a 45.9% increase. Most cases occurred in brown-skinned males aged 60-69. Most surgeries were elective. The Southeast region had the highest number of cases, while […]

ABSTRACT The aim of this case report was to demonstrate the importance of the neuro-ophthalmological examination, particularly the assessment of the pupillary reflex, in identifying neurological abnormalities in asymptomatic patients, highlighting its crucial role in the early detection of intracranial aneurysms, even in the absence of evident clinical signs. This is an observational, retrospective, and descriptive case report of a 70-year-old male patient with chronic glaucoma. During a routine ophthalmological evaluation, a relative afferent pupillary defect was identified in the […]

ABSTRACT Sturge-Weber Syndrome is a rare, non-hereditary developmental condition characterized by hamartomatous vascular proliferations affecting the brain and facial tissues. Its main features include corticocerebral angiomatosis, cerebral calcifications, epilepsy, ocular abnormalities, mental impairment, and a facial port-wine stain. This report aims to highlight the main features of Sturge-Weber Syndrome in a patient with unilateral facial and scalp nevus, ipsilateral glaucoma, and imaging alterations. A case study was conducted on a patient treated at an ophthalmology clinic. The diagnosis and follow-up […]

ABSTRACT This report aims to present classical and pathognomonic ocular changes, sequelae, and complications in a patient with Virchowian leprosy diagnosed in 2008 and undergoing their first ophthalmological evaluation in 2023. Leprosy is an infectious disease caused by Mycobacterium leprae, more prevalent in underdeveloped countries, with Brazil being the second most prevalent country worldwide. Cutaneous and peripheral nerve involvement are very common. However, ocular manifestations, which most frequently occur in patients with a long course of the disease in the […]

ABSTRACT Sturge-Weber syndrome is a rare sporadic and congenital neurocutaneous disease characterized primarily by the presence of cutaneous and extracutaneous capillary malformations. Our understanding of this syndrome has improved since its first description over the years, particularly with the identification of different clinical presentations and new genetic mutations. Ocular manifestations are frequently observed in this syndrome but often develop insidiously and can threaten visual prognosis. Thus, an appreciation of different ophthalmological manifestations seems crucial. In the same perspective, we report […]

ABSTRACT We present a case of a 66-year-old male patient with primary angle closure glaucoma who underwent cataract surgery. He was also under tamsulosin treatment for benign prostate hyperplasia. Due to high intraocular pressure and shallow anterior chamber, 150 mL of 20% mannitol was given intravenously, before phacoemulcification cataract surgery. The iris prolapsed from the main incision and the pupil constricted, right after the main incision was opened and the pupil shrank. An additional 150 mL of 20% mannitol was […]