ABSTRACT Objective: To evaluate whether an Artificial Intelligence model based on easily accessible perinatal variables can predict congenital ophthalmologic malformations, particularly those whose late detection may lead to preventable blindness. Methods: Retrospective diagnostic accuracy study using the DATASUS database. A total of 6,633 newborns in Brazil (2014 to 2022) were included, with 2,211 congenital ophthalmologic malformations (ICD-10 Q100-Q159) and 4,422 controls. Predictors comprised 14 maternal, obstetric, and neonatal factors; records with missing data were excluded. Logistic regression and support vector […]

ABSTRACT The aim of this case report was to demonstrate the importance of the neuro-ophthalmological examination, particularly the assessment of the pupillary reflex, in identifying neurological abnormalities in asymptomatic patients, highlighting its crucial role in the early detection of intracranial aneurysms, even in the absence of evident clinical signs. This is an observational, retrospective, and descriptive case report of a 70-year-old male patient with chronic glaucoma. During a routine ophthalmological evaluation, a relative afferent pupillary defect was identified in the […]

Purpose: To determine the frequency and clinical features of the extrinsic ocular motility changes in patients with multiple sclerosis living in the state of Sao Paulo (Brazil), consecutive cases series from 1996 to 2011. Methods: Eighty-three consecutive multiple sclerosis subjects were enrolled, aged from 17 to 59 years. All patients had a history taking and a comprehensive ocular exam. Results: Extrinsic ocular motility changes was detected in 17 (20,48%) out of 83 individuals. Diplopia as the first symptom of the […]