ABSTRACT Acute corneal hydrops is an ophthalmologic emergency resulting from rupture of Descemet’s membrane with entry of aqueous humor into the corneal stroma. Patients typically present with ocular pain, blurred vision, photophobia, and tearing. The main risk factors include trauma due to ocular itching, allergic keratoconjunctivitis, corneal ectasia, and Down syndrome. Although a rare complication, it is most commonly associated with keratoconus. Clinical treatment with eye drops should always be initiated, but in advanced cases, combined surgical intervention may be […]

ABSTRACT Introduction: Hyaluronan/hyaluronic acid based therapies are commonly used for treating corneal injuries in the clinic; however, there is a lack of consensus on whether hyaluronic acid promotes corneal wound healing. This systematic review critically evaluated peer-reviewed publications describing the clinical use of topical hyaluronic acid for treating corneal injuries. Methods: Unfiltered searches were conducted to identify peer-reviewed publications describing the clinical use of topical hyaluronic acid for treating various forms of corneal injuries using PubMed® and the University of […]

ABSTRACT Objective: To evaluate 1-year real-world results of effectiveness and safety of selective laser trabeculoplasty as an alternative to eye drops in patients with early to moderate open-angle glaucoma. Methods: This is a retrospective longitudinal study of a series of cases undergoing selective laser trabeculoplasty in patients with early to moderate open-angle glaucoma who were in use of topical anti-glaucoma therapy. The ability to reduce the intraocular pressure and the medication burden were evaluated, as well as the occurrence of […]

ABSTRACT Objective: To conduct a study on the logistics of business implementation and viability of autologous serum eye drops therapy. Methods: One-hundred seventy-seven (177) ophthalmology services/clinics/offices were identified in the Botucatu region (SP). Five physicians, who agreed to participate in the study, selected and monitored patients with indication for autologous serum eye drop use, following the requirements of serological analysis for blood-borne diseases. The batches were customized for each patient and are mostly issued every 3 months. Results: Half of […]

ABSTRACT We propose a novel surgical technique in cases of aggressive recurrent pterygium non-subsidiary of treatment with conjunctival autografts or antimetabolites. Two presented cases were treated with surgical excision and a sutured plasma rich in growth factors membrane (mPRGF) followed by rich in growth factors (PRGF) eye drops treatment. After surgery, dexamethasone, tobramycin and PRGF eye drops were prescribed for 6 weeks. After a 12-month and 3-year post-surgical follow-up respectively, treated eyes with mPRGF did not present relapse, and visual […]

Objetives: To assess the degree of fungal and bacterial contamination of hypotensive eye drops and the way these are preserved by the patients at the Glaucoma outpatient clinic of Santa Casa Hospital in Ribeirão Preto. Methods: Fifty-five patients were randomly assigned to follow-up in the outpatient clinic and, after their consent, an eye drop was collected per patient and later sent by mail for analysis by microbiologist and pathologist in up to 72 hours. Approximately 0.5ml of the medications were […]

Objective: Evaluate how difficult it is to apply ocular topical medications based on patient observation and answers to a questionnaire. Eye drops in open eyes were compared to vaporization in closed eyes. Methods: The study was a randomized clinical trial paired and held in the months of august and september of 2012 in the ophthalmological department of Polyclinic Ronaldo Gazolla (Arcos da Lapa Campus, Faculty of Medicine, University Estáciode Sá, RJ) in 50 patients. The Optive® ophthalmic solution was applied […]

OBJECTIVE: The objective of this study is to evaluate the cost of the use of lubricant eye drops, which are more used in the national market and contain in its formulation the same active ingredient – carboximeticelulose -, by considering their total number of drops in each flask. METHODS: An experimental study was accomplished by using three flasks of each one of the following eye drops: Lacrifilm®(eye drop 1) and Fresh Tears®(eye drop 2). To the analysis of their cost, […]