PURPOSE: To assess the efficacy of topical cyclosporine .05% for preventing endothelial loss in cornea transplant. METHODS: Retrospective study of 18 eyes submitted to penetrating transplant due to keratoconus, operation carried out by the same surgeon. Patients with specular microscopy with lower than or equal to 1200 cells/mm2 belonged to the control group. The inclusion criterion was the occurrence of specular microscopy in the postoperative period over the 6- month, 1- year, and 2- year periods and the exclusion criterion […]