Topiramate is a kind of sulfamate-substituted monosaccharide of oral presentation to be used primarily as an anticonvulsant and it doesn’t have structural relation with any other antiepileptic agents. This wide range antiepileptic drug has been used in the management of migraine, depression and neuropathic pain. Since it was approved as an anticonvulsant, many reports related to ophthalmological adverse effects have been published. The pathological findings include secondary angle closure glaucoma, transitory myopia, ocular hyperemia, uveal effusions, with or without mydriasis.

PURPOSE: Could the central corneal thickness (CCT) change the intraocular pressure (IOP) measured by ICARE (IC) GOLDMANN APPLANATION TONOMETER (GAT) and PASCAL DYNAMIC COUNTOUR TONOMETER (PDCT). METHODS: Before using the anesthesia we have measured the IOP with IC tonometer. After that we have used topical anesthesia to obtain the CCT using an ultrasound pachymeter (Mentor Co.) and the IOP measured by PCDT followed by a drop of fluorescein to measured IOP with GAT. RESULTS: 138 eyes of 71 patients were […]

PURPOSE:To identify the most important variables interfering with the correct topical administration of antiglaucomatous drugs. METHODS: Forty glaucomatous patients under clinical treatment were interviewed and observed while applying antiglaucomatous drugs. The following variables were analyzed: sex; age; income; washing of the hands; number of drops; motor abnormalities; availability of another person to apply the drug; place of the globe reached; bottle-eye contact; previous instruction; positioning for application; development of a burning sensation, pain or irritation. Using the questionary, the variables […]

PURPOSE: To compare measurements of central corneal thickness obtained using a Haag-Streit optic pachymeter and a DGH 500 (Pachette Ttm ) ultrasonic pachymeter in normal patients. METHODS: An evaluation was made of 200 eyes of 100 patients using Optic (PO) and Ultrasonic (PU) pachymeters. Measurements were made in the area of the central cornea (ECC) respecting the 3.0 mm territory, in patients with normal corneas of hypermetropic, emetropic and myopic eyes. Patients with ocular diseases, ocular surgeries, and contact lens […]

The aim of this article is to make a review about glaucoma associated with penetrating keratoplasty, describing since its incidence and risk factors until the different options for treatment.