The intraocular lenses have been used in visual rehabilitation after cataract surgery since 1959 with a large success. However, biomaterial changes in the optic zone of these lenses have been described in the last years reducing visual acuity after surgery. This case reveals a significant snowflake opacification of the optic zone of polymethylmethacrylate intraocular lens followed by a discussion about this event and the indication for IOL exchange.