Main reasons for discarding corneas for transplant in Paraíba: why does anti-HBc deserve attention?*

Esther Rocha de Queiroz

Alves

, Lara Fernandes de

Carvalho

, Camila Melo Gadelha Pereira

Diniz

DOI: 10.37039/1982.8551.20240003

ABSTRACT

Objective:

To identify the profile of human ocular tissue donors in the area covered by the Eye Bank of Paraíba (PB), highlighting the impact of positive serology for hepatitis B (anti-HBc) in the disposal of tissues for transplantation.

Methods:

This is a cross-sectional that uses data from the Eye Bank of Paraíba (PB) between January 2013 and December 2022. Data on origin, age, sex, cause of death, time between death and enucleation, serological results, and reason for discarded donor corneas were collected.

Results:

The main reason for discarding was due to positive serology (56.5%), with positive anti-HBc and HBsAg serology in 11.1% and 4.75% of patients, respectively.

Conclusion:

Anti-HBc positive serology as an absolute disposal criterion is responsible for great part of disposals, despite little information about its repercussions and representation of infectivity in transplant recipients.