ABSTRACT Bupthalmos is characterized by congenital enlargement of the eyeball due to uncontrolled glaucoma in early childhood, which is mostly caused by primary congenital glaucoma. Primary congenital glaucoma, the leading cause of childhood glaucoma, is typically inherited in an autosomal recessive manner and is a significant contributor to pediatric blindness. In contrast, cartilage-hair hypoplasia, another autosomal recessive disorder, presents with disproportionate short stature, increased malignancy risk, and immunological complications. This case report describes a rare co-occurrence of primary congenital glaucoma […]

ABSTRACT Objective: To critically review current therapeutic strategies for Sjögren’s syndrome (SS), emphasizing ocular and respiratory manifestations, and highlighting innovative interventions with clinical applicability. Methods: This is an integrative literature review based on the PICO strategy. A systematic search was conducted in the VHL, SciELO, MEDLINE, and LILACS databases, covering publications from 2020 to 2025. Controlled descriptors and free terms related to “Sjögren’s Syndrome,” “Interdisciplinary Approach,” and “Ocular Manifestations” were used to identify relevant scientific evidence on the multidisciplinary management […]

ABSTRACT Objective: To investigate the epidemiological profile of ocular toxoplasmosis in an ophthalmology hospital in western Paraná. Methods: A retrospective study conducted between 2015 and 2022 through the review of medical records, using the presence of chorioretinal scars as a presumptive diagnosis of ocular toxoplasmosis. Results: 3.03% of patients seen during the study period presented with presumptive ocular toxoplasmosis lesions, with a higher prevalence in women (57.25%) and in the age group of 60–79 years old (42.18%). Diabetes was observed […]

ABSTRACT Objective: The primary objective of this study was to characterize normal optic nerve parameters in Latin American patients using Optical Coherence Tomography (OCT) during the period from 2015 to 2022. Methods: A retrospective, cross-sectional, descriptive study was conducted using data retrieved from the database of the Exilaser Clinic in Cuenca, Ecuador. The study included 290 adult patients without ocular abnormalities. Data from each eye (left and right) were analyzed using SPSS software. For quantitative variables, measures of central tendency […]

ABSTRACT Normal-tension glaucoma (NTG) is a glaucomatous optic neuropathy that occurs in the absence of intraocular hypertension, and its pathophysiology is not solely dependent on pressure-related factors. Extrinsic mechanisms, such as autonomic dysfunction and microvascular hemodynamic alterations, have been implicated in its progression, with obstructive sleep apnea (OSA) standing out as an important contributing factor. We report the case of a patient with NTG and severe OSA confirmed by polysomnography, who exhibited progressive structural and functional loss despite controlled intraocular […]

Nipah virus (NiV) is a zoonotic RNA virus classified within the family Paramyxoviridae and the genus Henipavirus. It was initially discovered during an outbreak in Malaysia in 1998 and has since been associated with epidemics in various countries throughout South and Southeast Asia, frequently causing high fatality rates. Fruit bats belonging to the genus Pteropus act as the main natural reservoir, while human infection can lead to severe neurological and respiratory illnesses, representing a major public health concern.(-) The epidemiology […]

ABSTRACT Objective: To evaluate public knowledge of keratoconus in Brazil and identify gaps to guide future educational strategies. Methods: A cross-sectional online survey, based on the 2015 Global Consensus on Keratoconus, was distributed via social media and an ophthalmology bulletin. Adults (≥18 years) participated anonymously after providing informed consent. The questionnaire assessed demographics, ocular history, and keratoconus-related knowledge. Descriptive statistics summarized the data, and associations were analyzed using chi-square and nonparametric tests (5% significance level). Results: A total of 879 […]

ABSTRACT This systematic review and meta-analysis compared Manual Small Incision Cataract Surgery (MSICS) with phacoemulsification for the management of mature cataracts, evaluating outcomes such as visual acuity, surgical complications, endothelial cell loss, central corneal thickness, surgery duration, and cost-effectiveness. A comprehensive search was conducted across PubMed®, Web of Science, Embase, and the Cochrane Library through November 23, 2023, without language restrictions. Of 163 articles initially retrieved, five studies met the inclusion criteria, encompassing a total of 577 eyes. Pooled results […]