ABSTRACT Objective: To evaluate the incidence, epidemiological profile, risk factors, and severity of retinopathy of prematurity (ROP) in preterm newborns (PTNB) and very low birth weight (VLBW) infants at a university hospital. Methods: This was a retrospective cohort study using data from newborns admitted to the Neonatal Intensive Care Unit (NICU) between January 2014 and December 2022. Preterm newborns with birth weight ≤1500 g and/or gestational age ≤32 weeks were included. Maternal and neonatal information was analyzed. Results: A total […]

ABSTRACT Objective: To determine the evolution of retinopathy of prematurity in patients treated with intravitreal antiangiogenics in the retina private practice. Methods: A retrospective descriptive observational case series study was conducted. The study was non-experimental and non-probabilistic. Based on a population of 61 newborns, with a 99% confidence interval and a margin of error of 1%, the sample would be 61 newborns. The data from Google Sheets was transferred to CVS and then the Statistical Package for the Package Power […]

ABSTRACT Objective: To evaluate the incidence of retinopathy of prematurity and of its outcomes in a reference maternity hospital in northeastern Brazil and to identify associated factors. Methods: A cross-sectional, retrospective study was conducted using secondary data from newborns screened between August 2020 and November 2022. Results: The statistical analysis included 166 infants. The disease incidence was 40% (66 cases). Stage 2 was the most incident (46 cases), followed by stage 1 (15 cases) and stage 3 (5 cases). No […]

ABSTRACT This article presents the main recommendations and instructions necessary for ophthalmologists to organize a program to prevent blindness due to retinopathy of prematurity in both public and private hospitals.

ABSTRACT Retinal detachment related to retinopathy of prematurity is a surgical challenge, and vitrectomy can directly release transvitreal traction resulting from fibrous proliferation. The presence of iatrogenic breaks is a poor prognostic factor and has been considered a dismal prognosis. We report a case of premature female baby that underwent a 3-port 23-Gauge pars plana vitrectomy for stage 4A retinopathy of prematurity, with intraoperative progressive rhegmatogenous detachment complication. Lensectomy, extensive membrane dissection and vitreous shaving, followed by a posterior retinotomy, […]

ABSTRACT To describe the prevalence of risk factors for retinopathy of prematurity and respective stages. Retrospective data were extracted from original articles addressing risk factors for retinopathy of prematurity retrieved from Scientific Electronic Library Online (SciELO), Virtual Health Library (VHL) and National Library of Medicine – NLM (PubMed) databases. In the initial search, 186 articles were found. Following title and abstract reading and application of inclusion and exclusion criteria, 25 articles were selected for this analysis. Variables of interest varied […]

ABSTRACT Background: Retinopathy of prematurity (ROP) is a vasoproliferative retinal disorder that affects extremely premature infants and is the leading cause of irreversible blindness in childhood. Objective: This study presents a review of Cochrane systematic reviews about ROP. Methods: We analyzed and summarized the results of all intervention, prevention and treatment, from Cochrane Systematic Reviews (SR) for ROP designed to the highest standard of rigor to show the current position and propose studies that are missing for decision making. Results: […]

Objective: To evaluate the efficacy of an oxygen saturation reduction protocol used to supplement preterm newborns (PTNB) hospitalized in a neonatal ICU to prevent the onset of retinopathy of prematurity (ROP). Methods: This is a cohort study performed in a single Neonatal ICU. The first group (pre-protocol, n = 30) used oxygen with hemoglobin saturation > 95%. Since the institution of a new oxygen therapy protocol that maintained hemoglobin saturation between 90% and 95%, the second group was obtained (post-protocol […]