ABSTRACT Objective: To conduct a comprehensive analysis of the pathogenetic mechanisms through which various groups of allergens cause ocular manifestations. Methods: A systematic review of scientific publications from 2010 to 2024 is conducted, incorporating data from PubMed®, Scopus, Web of Science, and Google Scholar. The selection of literature is based on peer-reviewed studies with clear methodologies, ensuring a high level of result reliability. Results: The analysis demonstrates that the primary triggers of allergic conjunctivitis are aeroallergens, contact allergens, and food […]

ABSTRACT Purpose: To assess the agreement between IOLMaster 500 and Argos for ocular biometry parameters Methods: This retrospective study included 104 patients (205 eyes) who underwent biometry with both devices. Measurements included axial length (AL), keratometry (K1, K2), and ACD. Anterior chamber depth (ACD) measurements were compared directly as reported by each device, without additional correction for corneal thickness. Results: No significant differences were found for AL (23.49 ± 1.29 mm versus 23.63 ± 1.35 mm; p = 0.737), K1 […]

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ABSTRACT Objective: To evaluate the prevalence and severity of dry eye disease in patients with a history of COVID-19 infection. Methods: A total of 76 patients who had recovered from COVID-19 were included in the study. Dry eye disease was assessed using subjective and objective measures, including the Ocular Surface Disease Index questionnaire, tear break-up time, Schirmer test, and corneal staining. Results: This study included 76 patients with a mean age of 54.55 ± 10.61 years. The results revealed a […]

A 76 year-old woman presented with decreased visual acuity of the right eye. The patient has a known history of arterial hypertension and underwent surgery for bilateral cataracts 10 years prior. The best corrected visual acuity was 5/10 in the right eye and 10/10 in the left eye. Biomicroscopic examination revealed pseudoexfoliative fibrillar deposits attached to a pleated membrane on his lower nasal side (). This pseudoexfoliative membrane is attached to the anterior surface of the posterior chamber intraocular lens […]

ABSTRACT Objective: To investigate the impact of diabetic retinopathy on vision-related quality of life in patients with type 1 and type 2 diabetes mellitus in a Brazilian population. Methods: This cross-sectional study included patients aged over 18 years attending the Diabetes Outpatient Clinic of Santa Casa de Belo Horizonte between January and December 2022. Vision-related quality of life was assessed using the National Eye Institute Visual Function Questionnaire. Patients were classified into three groups according to diabetic retinopathy severity: mild […]

ABSTRACT Choroideremia is a rare X-linked chorioretinal dystrophy that may closely resemble retinitis pigmentosa (RP) in its early stages. We describe two brothers who were initially diagnosed with RP and later found to have choroideremia after multimodal imaging and genetic testing. The proband, a 49-year-old man, presented with progressive visual loss, diffuse chorioretinal atrophy, and bone spicule pigmentation. His 51-year-old brother had advanced disease with no light perception. Both displayed fundus autofluorescence and OCT findings typical of choroideremia. A hemizygous […]

ABSTRACT Objective: To evaluate the therapeutic response to brolucizumab in eyes with chronic neovascular age-related macular degeneration (nAMD) refractory to prior anti-angiogenic treatments. Methods: This prospective observational study included patients with chronic nAMD who maintained exudative neovascularization after at least three injections of ranibizumab and/or aflibercept without previous episodes of uveitis or vasculitis. Participants received one to three intravitreal injections of brolucizumab. Best-corrected visual acuity (BCVA) was assessed before and 4 weeks after each injection, along with analysis of fluid […]