Rev Bras Oftalmol.2026;85:e0019
Response to: Corneal collagen cross-linking by sun exposure and high dose oral riboflavin: a multicentric longitudinal observational study
DOI: 10.37039/1982.8551.20260019
Dear Editor,
We appreciate your thoughtful review of our recently published article. We fully agree that the ideal way to evaluate the potential of oral riboflavin combined with sun exposure would be through a prospective, controlled, large-scale study involving patients with documented progressive keratoconus. Only then would it be possible to unequivocally distinguish the effect of the intervention from natural variability, spontaneous stability, or co-interventions.
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Response to: Corneal collagen cross-linking by sun exposure and high dose oral riboflavin: a multicentric longitudinal observational study