We would like to stress the importance of adequate examination through direct ophthalmoscopy in the screening and management of patients with hypertension and diabetes; as mentioned in the article Retinopathy in patients with hypertension and/or diabetes in a family health unit, this test gives general practitioners more control over the clinical course of their patients and leads to more accurate referrals of patients to ophthalmologists(1) […].

Learning how to devise and conduct clinical studies can be an ambitious goal, but it is perfectly feasible. The most important step in this learning process is perhaps the initial reflection, which is the basis for planning each step of the training requirements, bearing in mind that even the great researchers have not learned overnight(1) […].

The biggest challenge of science is to add something new and practical to knowledge. On the other hand, one of the most common mistakes, responsible for the delay of the same science, is the lack of knowledge of what has been studied and published in literature. In general, in medicine, and particularly in ophthalmology, the technological, medical and surgical advances for the benefit of patients are unquestionable. Early diagnosis of glaucoma and of many retinal diseases has progressed remarkably due […]

Objective: To analyze the accuracy of the clinical examination in the diagnosis of eyelid lesions. Methods: From the observation of thirtyfive photos of benign and malignant eyelid tumors were presented to ophthalmologists, for each picture, it was asked 3 questions: 1) the lesion is malignant or not; 2) if considered malignant, the probably histological type; and 3) the tumor is aggressive or not. The phisicians were divided into 9 groups, according to academic degree (time since graduation and Oculoplastics specialty […]

Purpose: To measure and compare size and shape parameters of femtosecond laser capsulotomy with manually continuous curvilinear digital guided capsulorhexis (CCC) and their refractive outcomes. Methods: Laser capsulotomies in 40 eyes of 40 patients were performed using LenSx femtosecond laser device (Alcon, Forthworth, US) and its results were compared with the CCC digital guided carried out in 40 eyes of 40 patients using the Callisto Eye digital image system (Zeiss, Germany). Capsulorhexis circularity, shape and capsule overlap were measured using […]

Objective: Demonstrate the Brimonidine effect over Retinal Spreading Depression (SD). Brimonidine is an alpha-2–adrenergic receptor agonist, used in the management of glaucoma. Alpha2-agonists have been shown to be neuroprotective in various experimental models, however the molecular and cellular targets leading to these actions are still poorly defined. The SD of neuronal electric activity is a wave of cellular massive sustained depolarization that damages the nervous tissue. Local trauma, pressure, ischemic injuries and other chemical agents as high extracellular potassium concentration […]

Objetivo: Demonstrar o efeito do Tartarato de Brimonidina, um alfa2-agonista usado no manejo do glaucoma, sobre a depressão alastrante (DA) retiniana. Esses agonistas têm demonstrado ser neuroprotetores em vários modelos experimentais, contudo seus alvos celulares e moleculares continuam indefinidos. A DA da atividade elétrica neuronal é uma onda de despolarização celular massiva e sustentada que leva ao dano no tecido nervoso. Trauma local, pressão, isquemia e outros agentes químicos como o aumento do potássio extracelular e o glutamato podem disparar […]