ABSTRACT Objective: To assess the diagnostic accuracy of ChatGPT in analyzing OCT images. Methods: A total of 300 OCT images, previously interpreted by specialists, were analyzed by ChatGPT under three scenarios: image-only input; input with additional epidemiological data; and input with detailed clinical data. Sensitivity, specificity, and accuracy rates were compared across scenarios using appropriate statistical analyses (p < 0.05). Results: Overall accuracy was 66.33% in the image-only scenario, 82.33% with epidemiological data, and 92.67% with clinical data. Sensitivity for [...]

ABSTRACT The pachychoroid disease spectrum (PDS) encompasses a range of chorioretinal disorders characterized by increased choroidal thickness, dilated Haller’s layer vessels (pachyvessels), and choroidal hyperpermeability, often associated with retinal pigment epithelium (RPE) alterations. This review synthesizes current evidence on pachychoroid pigment epitheliopathy (PPE), central serous chorioretinopathy (CSC), pachychoroid neovasculopathy (PNV), and polypoidal choroidal vasculopathy (PCV), emphasizing their shared pathophysiological mechanisms, multimodal imaging features, and clinical implications. Enhanced depth imaging optical coherence tomography (EDI-OCT) and widefield indocyanine green angiography (ICGA) have […]

Abstract The purpose is to report the management of multiple retinal epithelial detachments (PEDs) in a 50-year-old male with bilateral PEDs not associated with chorioretinal or systemic pathologies after a complete study. Idiopathic multiple PEDs could be a variation of central serous chorioretinopathy, but other causes as well as other pathological conditions which could produce similar images, are required to be ruled out.

Objetive: To evaluate the association between sympathetic nervous system activity and blood pressure variability with central serous chorioretinopathy (CSC). Methods: We performed an individual, observational, and cross-sectional study involving 11 patients with CSC and 16 healthy individuals in similar age range. Participants underwent spectral power analysis of heart rate variability (HRV) at the Hypertension Department of Heart Institute at the University of São Paulo. Results: We demonstrated sympathetic activity predominance in CSC group and found that the LF (low frequency) […]

Objetivo: Avaliar a associação entre a atividade do sistema nervoso simpático e a variabilidade da pressão arterial com a coriorretinopatia serosa central (CSC). Métodos: Estudo individuado, observacional e transversal envolvendo 11 pacientes com CSC e 16 indivíduos saudáveis de idade semelhante. Os participantes foram submetidos à análise de poder espectral da variabilidade da freqüência cardíaca no Departamento de Hipertensão do Instituto do Coração da Universidade de São Paulo. Resultados: Observamos o predomínio da atividade simpática no grupo com CSC, evidenciado […]