ABSTRACT Objective: To describe the clinical benefits of intense pulsed light applied directly to the eyelids of patients with Meibomian gland dysfunction and without glandular expression. Methods: A paired, retrospective cohort involving 16 patients diagnosed with symptomatic Meibomian gland dysfunction according to the criteria of the 2011 International Workshop on Meibomian gland dysfunction and treated with Intense Pulsed Light. The patients received three biweekly sessions on the eyelids and with the Lumenis OPT M22™ equipment. Glandular expression was not performed […]

ABSTRACT Objective: To analyze visual performance in digitally active volunteers using ScCLs. Methods: ScCLs were fit in seven participants and evaluated during four visits over 45 consecutive days. Reading speed tests were performed with MNREAD-P charts and texts developed by the Department of Speech Therapy of the authors’ institution. Post-study, participants were interviewed and completed the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8). Results: During ScCL wear, 85.7% showed increased reading speed on MNREAD-P charts, with similar results on the […]

ABSTRACT Objective: To investigate clinical-epidemiological profile, risk factors, and quality of life of patients with meibomian gland dysfunction. Methods: A total of 108 patients were prospectively studied. Symptoms of dry eye, eyelid disorders and secretory function were analyzed. Laboratorial exams included fasting glucose, glycated hemoglobin, cholesterol, and triglycerides. Quality of life was analyzed using the Ocular Surface Disease Index©. Results: Mean age was 53.6 ± 17.9 years, 69.4% were females, 82.7% with gynecological history, 46.3% with cardiovascular history, and 80.6% […]

ABSTRACT Objective: To examine the relationship between hormonal changes, particularly estrogen, and lacrimal gland function in dry eye syndrome using a surgically induced menopausal rat model. Methods: Twenty-four female rats were divided into four groups: control, ovariectomized, ovariectomized with estrogen replacement, and ovariectomized with phytoestrogen replacement. Rats with regular estrous cycles were selected via vaginal cytology. Ovariectomy was performed on ovariectomized groups, and ovariectomized with estrogen replacement and ovariectomized with phytoestrogen replacement groups received hormonal interventions. Histological analysis assessed collagen […]

ABSTRACT Objective: To evaluate the tear film and dry eye symptoms before and after phacoemulsification. Methods: Fifty-one patients diagnosed with cataracts participated in this clinical study (55% female; 78% white; 71.2 ± 6.5 years old; without the use of lubricating eye drops) and underwent phacoemulsification at a hospital in Aparecida (SP). Tear film analysis was performed by the tear film break-up test and dry eye symptoms were assessed by the Ocular Surface Disease Index, both before surgery and 30 and […]

ABSTRACT Purpose Evaluate blue-violet light filter and additional power of +0.40 D in the near zone ophthalmic lenses, on convergence, accommodative functions, and symptoms of digital asthenopia (DA). Methods Randomized study in cross-over design conducted on 49 volunteers (age, 29 ± 5.5 years; male: female, 18:31). Each subject wore test (+0.40 D in the near zone) and control lenses (regular single vision) for 4 weeks in randomized order. Both lenses had a selective blue-violet light filter. A baseline measurement was […]

ABSTRACT With the advent of the pandemic scenario caused by SARS-CoV-2 in the beginning of the year 2020, a vast clinical picture was noticed among the infected individuals. Among the most common eye symptoms caused by Covid-19, dry eye (DE) has become quite prevalent in this environment. The narrative review study seeks to assess the risk factors associated with the emergence or intensification of DE conditions in the population during the pandemic period. A literature review showed the influence of […]

ABSTRACT Objective To describe the use of subconjuctival administration of the anti-tumor necrosis factor agent adalimumab for treatment of dry eye in patients with Sjögren’s syndrome, and to investigate conjunctival healing. Methods Prospective, nonrandomized, noncomparative interventional case series including consecutive patients with Sjögren’s syndrome and dry eye disease treated with subconjunctival adalimumab, who were refractory to conventional treatment. Patients with infectious ocular surface involvement or structural changes in the tear pathway or eyelids were excluded. Data recorded included age, sex, […]