ABSTRACT Objective: To examine the relationship between hormonal changes, particularly estrogen, and lacrimal gland function in dry eye syndrome using a surgically induced menopausal rat model. Methods: Twenty-four female rats were divided into four groups: control, ovariectomized, ovariectomized with estrogen replacement, and ovariectomized with phytoestrogen replacement. Rats with regular estrous cycles were selected via vaginal cytology. Ovariectomy was performed on ovariectomized groups, and ovariectomized with estrogen replacement and ovariectomized with phytoestrogen replacement groups received hormonal interventions. Histological analysis assessed collagen […]

ABSTRACT Objective: To assess the clinical-epidemiological profile of patients with eyelid trauma associated with lacrimal canaliculus laceration, factors related to trauma and surgical intervention, and to evaluate post-surgical anatomical and functional success. Methods: A retrospective and longitudinal analytical study was conducted, in which chart analysis was performed for patients with eyelid trauma and associated canalicular injury, who were operated on from January 1, 2015, to July 31, 2022. Patients were selected and contacted for in-person evaluation and tests to analyze […]

ABSTRACT Objective: To describe the clinical and epidemiological characteristics, surgical techniques, and results of the canalicular laceration treatment at our service. Methods: A retrospective study was carried out from January 2012 to June 2020, considering canalicular injuries operated at a reference center. Demographic data, lesion characteristics, surgical details, and treatment outcomes were obtained from electronic medical records and were statistically analyzed. Results: Twenty-six cases of people with canalicular lesions aged between 2 to 71 years old were included, of whom […]

Graft-versus-host Disease (GVHD) is a major complication with high morbidity and mortality rates on patients undergoing hematopoietic stem cell transplantation. The ocular involvement, named ocular GVHD, may affect all structures of the eyes, but the lacrimal unit (lacrimal glands and ocular surface) is the main target of the inflammatory response mediated by the donor T cells. The development of dry eye disease is the main clinical ocular manifestation, and the association of a variety of therapeutics options is necessary. The […]

Tumors of the lacrimal gland are rare in clinical practice. Among all of them, the most common epithelial tumor is the lacrimal gland pleomorphic adenoma, which is a benign indolent tumor that usually affects adults in the third and fourth decades of life. We present an unusual case of lacrimal gland pleomorphic adenoma. Its management, radiological findings and outcomes are also described, along with a brief review of the literature.

OBJECTIVE:To present our experience in endoscopic dacryocystorhinostomy, discussing the results with those found in the literature. METHODS: The material in this study consisted of sixteen surgeries performed in twelve patients followed between 2009 to 2011. We analyzed gender, age at surgery, etiology of dacryocystitis, clinical features, number of surgeries required to repair, follow-up. RESULTS: There was a predominance of females compared to males (5:1) aged between 8 and 71 years, mean35.2 years. With regard to etiology, eight were classified as […]

PURPOSE: To evaluate the results of occlusion of the lacrimal punctum reversible with the use of thermosensitive plugs to treat the dysfunctional tear syndrome. METHODS: Eighteen eyes of 9 patients with dry eye were selected and subjected to reversible occlusion of the lacrimal punctum with the use of thermosensitive plugs and were followed for 60 days through the OSDI questionnaire, fluorescein staining, rose bengal staining and Schirmer’s test. RESULTS: in all studied patients there was improvement in dry eye symptoms […]