ABSTRACT This study shows an unusual case report of corneal ulcer caused by the fungus talaromyces marneffei, highlighting its clinical presentation, diagnosis, and therapeutic management. A 53-year-old male patient, immunocompetent, presented to ophthalmic care with complaints of ocular pain and decreased vision in the right eye. Examination revealed a central infiltrative corneal ulcer, with microbiological cultures identifying talaromyces marneffei, a rare occurrence in ocular infections. Initial treatment included antibiotic and antifungal eye drops, later adjusted to systemic antifungal therapy. After […]

ABSTRACT To describe a case of treatment-resistant corneal infiltrate in a patient 4 months after penetrating keratoplasty. The etiological diagnosis was established through microbiology and in vivo corneal confocal microscopy. A 80-year-old female patient presented with stromal infiltrate in the donor corneal bud 4 months following penetrating keratoplasty. Initially, the corneal culture was positive for Candida parapsilosis. In vivo corneal confocal microscopy demonstrated approximately 4 μm hyperreflective spherical microorganisms with a suggestive Candida spp. A second corneal culture was positive […]

Abstract Purpose: To report etiological diagnosis, predisposing risk factors, therapeutic strategies and visual outcome of patients treated at the Department of Ophthalmology of Federal University of São Paulo. Methods: This is a retrospective, descriptive, and observational study from medical and laboratory records of the Department of Ophthalmology of Federal University of São Paulo, including all patients with culture proven fungal keratitis in 5 years, from October 2012 through October 2017. Results: There were 2260 fungi microbiologic test requests. Of these, […]