Objective: To evaluate the occurrence of a mutation in candidate genetic loci and its relation with keratoconus in patients treated in Brazil compared to healthy volunteers, through analysis of single nucleotide polymorphism in the DOCK9 gene. Methods: In this clinical study, 108 participants were evaluated, including 46 keratoconus patients and 62 healthy volunteers (controls). DNA samples were extracted from collected blood from keratoconus patients and controls. The genotyping of the single nucleotide polymorphism rs7995432 in the DOCK9 gene was determined […]

O cross-linking corneano é utilizado com o objetivo de reduzir e estabilizar a progressão das patologias ectásicas através de seus efeitos na biomecânica da córnea. Diferentes protocolos estão sendo realizados pelo mundo para expandir suas indicações, assim como seu uso em diversas faixas etárias, diferentes estágios da doença, combinações com outras técnicas, além de utilizações para doenças não ectásicas. Não há ainda um consenso nas indicações do procedimento de cross-linking, mas os resultados publicados na literatura evidenciam mudanças significativas nas […]

The corneal cross-linking has been used in order to reduce and stabilize the progression of ectatic diseases through its effects on the biomechanics of the cornea. Different protocols are being conducted worldwide to expand its indications as well as its use at different ages, different stages of the disease, combinations with other techniques, besides the utilization for non-ectatic diseases. There is still no consensus on the indications of the cross-linking procedure, but the results published in the literature show significant […]

Purpose: To define the epidemiological aspects of the patients submitted to keratoplasty in the state of Santa Catarina, Brazil and the main indications for this procedure. Methods: We conducted an observational, descriptive and retrospective study with the data of 1161 patients submitted to cornea transplantation from january 2008 to december 2010, at the Transplantation Center of Santa Catarina. The analyzed data were: age, gender, origin, transplant date, indication and transplanted eye. Results: The mean age was 45.51 years and men […]

The intrastromal corneal ring implant surgery is becoming a surgical procedure in the treatment of keratoconus additive in order to minimize and delay the complications inherent to the pathology. Its action consists in the remodeling cornea, flattening and regulating the central corneal surface. Nowadays with the advent of new technologies, there is an important contribution in the diagnosis of keratoconus, with not only diagnosis but also more effective with better monitoring and prognosis of patients with this disorder ectatic. In […]

We present a case of late high progressive astigmatism following penetrating keratoplasty for keratoconus, which was associated with peripheral thinning in the donor-receptor area, which may be recognized as recurrence of ectasia. Treatment was accomplished with Cvintal’s Topoplasty assisted by femtosecond laser for a “top hat”, followed by resuture with peroperative adjustment guided by ceratoscopy.

OBJECTIVE: To evaluate the safety of PRK in patients with atypical corneal topography, but without features of keratoconus in Pentacam. METHODS: Medical records of patients who underwent PRK method that presented atypical corneal topography and Pentacam rates considered normal in the pre operative were analyzed. The sample consisted of nineteen eyes of ten patients. The considered criteria of corneal irregularity were: increased curvature greater than 47D with asymmetry less than 1,5D, 1,5D displacement above the apex and inferior-superior asymmetry greater […]

The methodology currently used for interpretation of the cornea and anterior segment tomography for the diagnosis of corneal ectasia. Description of the clinical interpretation of anterior segment tomography (Pentacam – Oculus, Wetzlar, Germany); case report of the ectopia lentis demonstrating the importance o evaluation of the cornea and anterior segment of the keratoconus. We excluded the disease, analyzing the tomographic analysis of rates of ectasia and observe an asymmetry between nasal and temporal sides in assessing the depth map of […]