ABSTRACT Diabetic retinopathy is the leading cause of vision loss among working-age adults in the Western world. Although it has traditionally been considered a microvascular disease, growing evidence suggests that neurodegenerative changes may occur even before the appearance of microvascular damage. The aim of this review was to provide a comprehensive summary of the current evidence regarding neurodegenerative changes in diabetic retinopathy. This is a narrative review, in which we performed a comprehensive literature search from August 15, 1998, to […]