OBJECTIVE: This study aims at observing the inhibition of cell proliferation in primary pterygium by the use in vitro of mitomicyn C, cyclophosphamide, methotrexate. METHODS: Pterigyum was removed from seven pacients between 30 and 60 years and were submitted to culture of epithelial cells. Later the effect of drugs was tested on the cells: cyclophsphamide, methotrexate, mitomicyn. The cells were observed for five days under the microscope to assess cellular proliferation, and the experiments were repeated five times RESULTS: When […]