ABSTRACT A 27-year-old healthy man with a history of bilateral photorefractive keratectomy (PRK) enhancement after femtosecond laser in situ keratomileusis (LASIK) presented with decreased uncorrected distance visual acuity (UDVA) of 20/125 in the right eye (OD) and 20/300 in the left eye (OS) six months after PRK. Examination revealed bilateral dense subepithelial opacities. Both eyes (OU) were treated with superficial keratectomy combined with phototherapeutic keratectomy (PTK) and adjunctive application of mitomycin C 0.02%. At three months follow up UDVA was […]

Over the years, mitomycin C has been used by refractive surgeons to prophylactically decrease haze after surface ablation procedures and therapeutically in the treatment of preexisting haze. Development of mitomycin C treatments has had a significant role in the revival of surface ablation techniques. We reviewed the literature regarding mechanism of action of mitomycin C, its role in modulating wound healing after refractive surgery, and its safety and efficacy as adjuvant therapy applied after primary photorefractive keratectomy surgery or after […]

Objective: To compare the influence of two techniques for corneal epithelial removal in photorefractive keratectomy (PRK) – blunt scrape versus rotary brush – regarding duration of technique application, intraoperative comfort, and reepithelization. Methods: This prospective randomized study included 58 eyes of 29 patients that underwent simultaneous and sequential PRK in both eyes – blunt scrape (scraped group) in one eye and rotary brush (brushed group) in the fellow eye. Results: The faster technique, measured in seconds, was the rotary brush […]