ABSTRACT Objective: To evaluate the red reflex test in children with congenital Zika syndrome in order to predict the occurrence of retinal lesion or optic nerve hypoplasia in these patients. Methods: A descriptive cohort study was conducted in children with Congenital Zika Syndrome. The red reflex test was performed with a direct ophthalmoscope, and it was repeated after pupils’ dilation. The patients underwent a comprehensive ophthalmological evaluation. Eye fundus was analyzed by binocular indirect ophthalmoscopy. The occurrence of macular atrophy […]

ABSTRACT Objective: To investigate clinical-epidemiological profile, risk factors, and quality of life of patients with meibomian gland dysfunction. Methods: A total of 108 patients were prospectively studied. Symptoms of dry eye, eyelid disorders and secretory function were analyzed. Laboratorial exams included fasting glucose, glycated hemoglobin, cholesterol, and triglycerides. Quality of life was analyzed using the Ocular Surface Disease Index©. Results: Mean age was 53.6 ± 17.9 years, 69.4% were females, 82.7% with gynecological history, 46.3% with cardiovascular history, and 80.6% […]

ABSTRACT Objective: To evaluate the impact of selective laser trabeculoplasty (SLT) on resource savings and medication costs. Methods: Retrospective study of patients with open-angle glaucoma (OAG) who underwent SLT as a replacement therapy for eye drops and were followed for up to 1 year. The ability to reduce intraocular pressure (IOP) and the amount of eye drops were evaluated, as well as the monthly cost of medications during the follow-up. The annual cost of medications was also calculated. The results […]

ABSTRACT Objective: To analyze the diabetic autonomic neuropathy through the comparison between the pharmacological mydriasis in patients without diabetes and with type 2 diabetes. Methods: This is an observational, cross-sectional, case-control study. The patients were dilated with phenylephrine 10% and tropicamide 1% eye drops. They were divided into patients without diabetes mellitus (Control or Group Zero) and patients with type 2 diabetes mellitus (Case Group). These patients with diabetes were divided into six groups according to the international classification of […]

ABSTRACT Objective: To assess the knowledge of healthcare professionals about corneal biomechanics in glaucoma and identify knowledge gaps for educational focus. Methods: A cross-sectional observational study involving an online questionnaire addressing knowledge and the importance of corneal biomechanics in glaucoma patients, completed by volunteer ophthalmologists, glaucoma specialists, and physicians from other specialties residing in Brazil. Data analysis was based on knowledge about the subject in these three groups, and the analyses were performed using the Statistical Package for Social Sciences, […]

ABSTRACT Objective: To evaluate theoretical knowledge of medical students, medical residents and general medicine specialists in fundus examination. Methods: This cross-sectional study included three groups: third year medical students, interne medicine residents and general medicine specialists. The selection was based on the expected proficiency for each of the groups. Participants were invited by email. Two questionnaires previously translated and validated to Portuguese were applied: one to evaluate self-confidence with fundus examination with a 5-item Likert scale and a second to […]

ABSTRACT Objective: To characterize the morphological aspects related to the integrity of the corneas. Methods: A biomicroscopic analysis of the corneas collected from January 2019 to January 2021, by the Human Eye Tissue Bank of Hospital João XXIII, in order to identify the main changes that led to their discarding, based on the medical records analyzed. Results: Almost all variables coincided with what the literature indicates; however, stromal infiltration manifested differently. Conclusion: The main discarding factors were epithelial exposure, epithelial […]

ABSTRACT Objective: To examine the relationship between hormonal changes, particularly estrogen, and lacrimal gland function in dry eye syndrome using a surgically induced menopausal rat model. Methods: Twenty-four female rats were divided into four groups: control, ovariectomized, ovariectomized with estrogen replacement, and ovariectomized with phytoestrogen replacement. Rats with regular estrous cycles were selected via vaginal cytology. Ovariectomy was performed on ovariectomized groups, and ovariectomized with estrogen replacement and ovariectomized with phytoestrogen replacement groups received hormonal interventions. Histological analysis assessed collagen […]