The biostatistics has gained significant importance in recent years, being one of the mainstays of current scientific research. It has a series of concepts and rules that must be understood to carry out or analyze an article. In this review we will discuss some of main tools utilized in works of interest in ophthalmology, its applications and limitations.
Biostatistics: fundamental concepts and practical applications
(A) Fundus photography of the right eye showing a circumscribed yellow-orange choroidal mass located along the inferotemporal vascular arcade. (B) Optical coherence tomography (OCT) demonstrating a dome-shaped choroidal mass with subretinal fluid, retinal pigment epithelium alterations, cystoid macular edema, and outer retinal damage.
LopesB, RamosICO, RibeiroG, CorreaR, ValbonBF, LuzAC, SalomãoM, et al. Biostatistics: fundamental concepts and practical applications. Rev Bras Oftalmol. 2014;73(1):16-22.
Lopes,Bernardo; Ramos,Isaac Carvalho de Oliveira; Ribeiro,Guilherme; Correa,Rosane; Valbon,Bruno de Freitas; Luz,Allan Cezar da; Salomão,Marcella; Lyra,João Marcelo; Ambrósio Junior,Renato. Biostatistics: fundamental concepts and practical applications. Rev Bras Oftalmol., v. 73, n. 1, p. 16-22, Jan. 2014.
Lopes,B., Ramos,I.C.O., Ribeiro,G., Correa,R., Valbon,B.F., Luz,A.C. , Salomão,M., Lyra,J.M., & Ambrósio Junior,R. (2014). Biostatistics: fundamental concepts and practical applications. Rev Bras Oftalmol.,73(1), 16-22.
Lopes,Bernardo and Ramos,Isaac Carvalho de Oliveira and Ribeiro,Guilherme and Correa,Rosane and Valbon,Bruno de Freitas and Luz,Allan Cezar da and Salomão,Marcella and Lyra,João Marcelo and Ambrósio Junior,Renato. Biostatistics: fundamental concepts and practical applications. Rev Bras Oftalmol. [online]. 2014, vol. 73, n. 1, [cited 2026-10-22], pp.16-22. Available from: <https://www.rbojournal.org/en/article/biostatistics-fundamental-concepts-and-practical-applications/>. ISSN 0034-7280.