Rev Bras Oftalmol.2025;84:e0057
Ligneous keratoconjunctivitis: a case report with predominantly corneal presentation
DOI: 10.37039/1982.8551.20250057
ABSTRACT
Ligneous conjunctivitis is a rare chronic disease described as membranous keratoconjunctivitis that may be associated with systemic manifestations. It is associated with congenital plasminogen deficiency. In this case report, we describe the case of a 3-year-old male child who was diagnosed with ligneous conjunctivitis that mimicked gonococcal conjunctivitis after secondary infection with Streptococcus pyogenes. The patient had a bilateral pre-tarsal conjunctival membrane and a fibrous membrane extremely adherent to the corneal epithelium in the left eye, associated with intense purulent sensation. A plasminogen activity test was performed using a result of 36%, with the reference value being between 75 and 150%. The treatment consisted of 14 sessions of plasmapheresis, resulting in an improvement in the appearance of the cornea and conjunctiva.”
