Cornea intraepithelial dysplasias are lesions with low risk of malignancy within the spectrum of intraepithelial neoplasia of the ocular surface. These areas are presented as dysplasias or leukoplasias and are associated with the presence of human papillomavirus (HPV), a major risk factor. In this report, the authors describe a case of a corneal intraepithelial dysplasia treated by surgical excision, with histological confirmation and negative DNA hybridization for HPV.
Negative hybrid capture in a single intraepithelial corneal dysplasia
MartinLFT, Bonini FilhoMA, OdashiroAN, GemperliL, GemperliDB, RochaEM, PaulaJS. Negative hybrid capture in a single intraepithelial corneal dysplasia. Rev Bras Oftalmol. 2010;69(2):125-8.
Martin,Luiz Fernando Taranta; Bonini Filho,Marco Antonio; Odashiro,Alexandre Nakao; Gemperli,Lizabel; Gemperli,Daniela Barbosa; Rocha,Eduardo Melani; Paula,Jayter Silva de. Negative hybrid capture in a single intraepithelial corneal dysplasia. Rev Bras Oftalmol., v. 69, n. 2, p. 125-128, Apr. 2010.
Martin,L.F.T., Bonini Filho,M.A., Odashiro,A.N., Gemperli,L., Gemperli,D.B., Rocha,E.M., & Paula,J.S. (2010). Negative hybrid capture in a single intraepithelial corneal dysplasia. Rev Bras Oftalmol.,69(2), 125-128.
Martin,Luiz Fernando Taranta and Bonini Filho,Marco Antonio and Odashiro,Alexandre Nakao and Gemperli,Lizabel and Gemperli,Daniela Barbosa and Rocha,Eduardo Melani and Paula,Jayter Silva de. Negative hybrid capture in a single intraepithelial corneal dysplasia. Rev Bras Oftalmol. [online]. 2010, vol. 69, n. 2, [cited 2026-03-07], pp.125-128. Available from: <https://www.rbojournal.org/en/article/negative-hybrid-capture-in-a-single-intraepithelial-corneal-dysplasia/>. ISSN 0034-7280.