Rev Bras Oftalmol.2025;84:e0047
Ocular perfusion pressure response during resistance exercise in healthy individuals: systematic review and meta-analysis
DOI: 10.37039/1982.8551.20250047
ABSTRACT
Objective:
To identify the acute effect of resistance exercise on ocular perfusion pressure (OPP) in healthy individuals.
Methods:
The recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses were used. Searches were conducted in the databases: Medline, Embase, Cochrane, CINAHL, Web of Science, and Scopus. Studies that assessed OPP before and after physical exercise were included. The risk of bias was analyzed by the Quality Assessment Tool for Before-After (Pre-Post) Studies with No Control Group. Random effect meta-analyses were conducted to determine the effect of handgrip and squatting physical exercises on OPP.
Results:
A total of 1,414 studies were found, of which 14 were eligible. After resistance exercise, an increase in OPP was observed after handgrip exercise (11.94 mmHg; 95% CI = 5.54 −18.33; I2= 93.74%; p < 0.01) and after squatting exercise (36.66%; 95% CI = 29.04-44.08; I2= 80.48%; p < 0.01), however, without major changes in ocular blood flow.
Conclusion:
Moderate resistance exercise increases OPP in healthy individuals. However, resistance exercises performed until concentric muscular failure seems to decrease this variable.
