Rev Bras Oftalmol.2025;84:e0049
Unilateral optic neuritis associated with MOG antibodies in a pediatric patient
DOI: 10.37039/1982.8551.20250049
ABSTRACT
Case report of a 14-year-old male presented with acute painless vision loss and left optic disc swelling. Extensive diagnostic investigations, including magnetic resonance imaging and serum MOG antibody testing, were conducted. Magnetic resonance imaging showed an extensive T2 hyperintense signal in the anterior portion of the left optic nerve without involving chiasm or retrochiasmatic areas. The management strategy involved intravenous methylprednisolone followed by azathioprine, resulting in complete vision recovery. This case highlights the importance of considering MOG antibody-associated optic neuritis in the differential diagnosis of acute vision loss in adolescents and discusses the clinical and imaging features that should prompt testing for anti-MOG antibodies.
Keywords: Adolescent; Azathioprine; Blindness; Methylprednisolone; Vision loss
