Rev Bras Oftalmol.2026;85:e0050
Normal-tension glaucoma associated with obstructive sleep apnea: case report of progression under controlled intraocular pressure
DOI: 10.37039/1982.8551.20260050
ABSTRACT
Normal-tension glaucoma (NTG) is a glaucomatous optic neuropathy that occurs in the absence of intraocular hypertension, and its pathophysiology is not solely dependent on pressure-related factors. Extrinsic mechanisms, such as autonomic dysfunction and microvascular hemodynamic alterations, have been implicated in its progression, with obstructive sleep apnea (OSA) standing out as an important contributing factor. We report the case of a patient with NTG and severe OSA confirmed by polysomnography, who exhibited progressive structural and functional loss despite controlled intraocular pressure. This case highlights the importance of screening and interdisciplinary management of OSA as part of the diagnostic and therapeutic approach to NTG.
Keywords: Glaucoma; obstructive; Optic nerve diseases; Polissonografia; Sleep apnea
