Rev Bras Oftalmol.2026;85:e0103
Secondary cataract following Nd:YAG laser due to dense inflammatory membrane in a young patient with HLA-B27-associated spondyloarthritis
DOI: 10.37039/1982.8551.20260103
ABSTRACT
Case Report:
A 35-year-old woman with a known history of HLA-B27–positive ankylosing spondylitis presented with pain and redness in the right eye. Ophthalmological examination revealed a dense central inflammatory membrane with severely reduced visual acuity. Anterior segment optical coherence tomography (AS-OCT) demonstrated crystalline material obstructing the trabecular meshwork. The patient underwent phacorefractive surgery with intraocular lens implantation, achieving significant visual improvement.
Conclusion:
Inflammatory ocular conditions associated with HLA-B27 may lead to unusual secondary iatrogenesis cataract formation after Nd:YAG laser treatment. Early recognition and appropriate surgical management can result in excellent visual outcomes.
Keywords: Cataract; HLA-B27 antigen; Lasers, solid-state; Spondylitis ankylosing

