ABSTRACT The objective was to investigate the efficacy of topical losartan in treating corneal scars in patients with varying clinical backgrounds. A case series with six patients diagnosed with corneal scars resulting from herpetic keratitis or complicated photorefractive keratectomy were treated with topical losartan at a concentration of 0.8 mg/mL. Each patient underwent comprehensive ophthalmologic evaluations, including anterior segment optical coherence tomography and corneal tomography, to assess clinical outcomes after treatment. Improvement in visual acuity was noted in five out […]

CASE REPORT […]

ABSTRACT Objective: To review the clinical and pathological aspects of CC secondary to infections by syphilis, toxoplasmosis, rubella, cytomegalovirus, herpes simplex. Methods: This is a literature review. Articles from journals indexed to PubMed, COCHRANE, LILACS, EMBASE and SCIELO from 2010 to 2023 were included. Results: A total of 45 articles were found, which, after selection, remained in 9 articles. Some articles were included to enrich the discussion in this topic. The infection caused by syphilis is related to corneal changes. […]

ABSTRACT Peripheral ulcerative keratitis (PUK) is an immune-mediated corneal infiltration associated with autoimmune diseases and systemic inflammation. Commonly associated with rheumatoid arthritis, it may also be associated with other rheumatologic, inflammatory, and infectious diseases. PUK is usually unilateral and peripheral, due to its proximity to the conjunctival vasculature. There is usually an epithelial defect overlying the infiltrate and the associated stromal thinning. The objective of this case report is to address one of the possible etiologies of PUK associated with […]

The acute retinal necrosis is a rare and devastating necrotizing retinitis, which can be caused by the herpes simplex virus type 1 or 2. It typically affects healthy patients of all ages. This study report a case of 18 year-old healthy male patient, with the the diagnosis of the acute retinal necrosis due to herpes simplex, and presents its clinical and ultrassonographic features. The acute retinal necrosis results in endofthalmitis because of lack of early diagnosis and therapy.