ABSTRACT This study aimed to identify and analyze the most recent scientific evidence on best practices for the administration of intravitreal injections, with particular focus on the setting (medical office versus operating room), same-day bilateral administration, and strategies to prevent complications. A literature review was conducted across Medline Complete, Scopus, Web of Science, and Google Scholar databases (2015–2025), using three distinct search strategies. Studies addressing guidelines and protocols, administration setting, and bilateral procedures were included. Data selection and analysis were […]