ABSTRACT Objective: To examine the relationship between hormonal changes, particularly estrogen, and lacrimal gland function in dry eye syndrome using a surgically induced menopausal rat model. Methods: Twenty-four female rats were divided into four groups: control, ovariectomized, ovariectomized with estrogen replacement, and ovariectomized with phytoestrogen replacement. Rats with regular estrous cycles were selected via vaginal cytology. Ovariectomy was performed on ovariectomized groups, and ovariectomized with estrogen replacement and ovariectomized with phytoestrogen replacement groups received hormonal interventions. Histological analysis assessed collagen […]

ABSTRACT Objective: To evaluate 1-year real-world results of effectiveness and safety of selective laser trabeculoplasty as an alternative to eye drops in patients with early to moderate open-angle glaucoma. Methods: This is a retrospective longitudinal study of a series of cases undergoing selective laser trabeculoplasty in patients with early to moderate open-angle glaucoma who were in use of topical anti-glaucoma therapy. The ability to reduce the intraocular pressure and the medication burden were evaluated, as well as the occurrence of […]

ABSTRACT Objective To assess the best illumination for low vision patients of a vision rehabilitation center. Methods A cross-sectional observational study was conducted with patients aged 10 years and older, visual acuity < 20/60 and ≥ 20/200 on the best eye. Four types of lamps of power equivalent to 60 W (halogen, warm LED, daylight LED and white LED). All of them were used in standardized fixtures, and the analysis was performed during the reading activity. The first step included [...]

ABSTRACT Objective: To identify, care for and report on the experience of combating visual disorders of schoolchildren in the countryside of Bahia. Methods: Experience report on visual triage, using the Snellen table, conducted in public schools with students from the 2nd to the 4th grade of elementary school in the city of Feira de Santana (Bahia). Referral criteria for ophthalmological consultation were Detection of visual acuity equal to or less than 20/30 in one eye; presence of complaints or external […]

ABSTRACT Objective: To conduct a study on the logistics of business implementation and viability of autologous serum eye drops therapy. Methods: One-hundred seventy-seven (177) ophthalmology services/clinics/offices were identified in the Botucatu region (SP). Five physicians, who agreed to participate in the study, selected and monitored patients with indication for autologous serum eye drop use, following the requirements of serological analysis for blood-borne diseases. The batches were customized for each patient and are mostly issued every 3 months. Results: Half of […]

ABSTRACT Objective: To evaluate the immediate effectiveness of intense regulated pulsed light applied to the periocular area of patients with dry eyes in a retrospective study of a series of cases. Methods: Seventy-six participants underwent intense regulated pulsed light therapy, consisting of light pulses applied to both periocular areas. In addition to a comprehensive ophthalmological examination, tear osmolarity measurements were taken for both eyes. Participants were also administered the Ocular Surface Disease Index (OSDI) questionnaire. Data were collected at baseline […]

ABSTRACT Objective: To report the frequency of ocular manifestations in patients undergoing direct-acting antiviral therapy and assess treatment safety based on outcomes; to identify demographic variables associated with hepatitis C virus infection; evaluate treatment effectiveness through sustained virological response. Methods: A prospective cohort study was conducted involving chronic hepatitis C patients undergoing direct-acting antiviral therapy. Ophthalmological evaluations were conducted before treatment initiation and upon completion. Patients were advised to return in case of any visual symptoms. Results: The study comprised […]

ABSTRACT Objective: To assess the prevalence of congenital ophthalmic malformations in Brazil between 2013 and 2021 and study the factors related to their occurrence in live births during this period. Methods: This was an epidemiological, observational, analytical, cross-sectional study using data from the Sistema de Informações sobre Nascidos Vivos on live births between January 2013 and December 2021 in Brazil. Only live births born with ≥ 500g were included in the study. Congenital ophthalmic malformations were analyzed according to the […]