A 77 year-old female patient suffering from pyelonephritis developed bilateral endogenous endophthalmitis presumed by Candida after have been treated with global spectrum antibiotics. Early vitrectomy and intravitreal amphotericin B injection were performed, in addition to oral voriconazole. Clinical aspects of endogenous endophthalmitis are also pointed out by a literature review.
A: Color fundus photography - when the patient was hospitalized - showing multiple white infiltrative lesions with vitreous extension (cotton balls colony) in both eyes. It is possible noticing several intraretinal hemorrhages in the right eye. Figure 1B: OCT - when the patient was hospitalized - showing increased retinal thickness and a lesion involving the choroid, with extension to the intraretinal layers in both eyes and apparent extraretinal migration to the vitreous
Caiado,Anna Victoria Porfirio Ramos; Morato,Rodrigo Macioca; Silva,Camilla de Magalhães Nardelli; Kobal,Christiane Reis; Diniz,Bruno. Bilateral endogenous fungal endophthalmitis. Rev Bras Oftalmol., v. 79, n. 4, p. 266-269, Sep. 2020.
Caiado,Anna Victoria Porfirio Ramos and Morato,Rodrigo Macioca and Silva,Camilla de Magalhães Nardelli and Kobal,Christiane Reis and Diniz,Bruno. Bilateral endogenous fungal endophthalmitis. Rev Bras Oftalmol. [online]. 2020, vol. 79, n. 4, [cited 2026-03-11], pp.266-269. Available from: <https://www.rbojournal.org/en/article/bilateral-endogenous-fungal-endophthalmitis/>. ISSN 0034-7280.