Case Report March 25, 2026 March 25, 2026

Eyelid pilomatrixoma: morphological features, clinical rarity, and diagnostic pitfalls in ophthalmologic practice

DOI: 10.37039/1982.8551.20260023

ABSTRACT

Pilomatrixoma is a rare benign neoplasm derived from hair matrix cells, with a preference for the head and neck region, especially in children and adolescents. Its occurrence in adults, particularly in the eyelid, is uncommon and often leads to misdiagnosis. Clinically, it presents as a firm, painless, subcutaneous nodule with progressive growth. Definitive diagnosis is established through histopathological examination, and the standard treatment is complete surgical excision, with low recurrence rates. This article describes a case of eyelid pilomatrixoma in a young adult, highlighting its morphological features, clinical rarity, and diagnostic challenges in ophthalmologic practice.