PURPOSE: To analyze effects of isosorbide dinitrate (DNI) on corneal hyperalgesia and neutrophil infiltration in an experimental model of superficial keratitis induced by lipopolysaccharide (LPS). METHODS: Hyperalgesia was studied through the induction of inflammatory keratitis in rats (n=60), by corneal exposure to LPS. Following exposure, the inflamed eye was treated for four days, with one of the following solutions: topical DNI (200 μg, 65 μg and 20 μg), prednisolone 1% (PRED), and vehicle. Saline-exposed eyes (LPS -) underwent the same […]

This is a case report of a 45-year-old anisometropic woman with stage 2 keratoconus submitted to refractive lens exchange employing SN60T5 AcrySof Toric intraocluar lens on her left eye. Phacoemulsification followed by proper lens implantation was accomplished successfully. On postoperative period, favorable refractive and visual outcomes were obtained. The use of toric intraocular lenses may be an option in the refractive treatment of stage 2 keratoconus in selected cases.

Relatamos o caso de uma senhora de 45 anos de idade, portadora de ceratocone grau 2 e consequente anisometropia, submetida à extração do cristalino transparente, e uso da lente intraocular modelo SN60T5 AcrySof Toric para o olho esquerdo. Facoemulsificação seguida pelo implante da lente intraocular tórica no olho esquerdo. No pós-operatório, resultados refracionais e visuais satisfatórios foram alcançados. O uso de lentes intraoculares tóricas pode se constituir em opção terapêutica para casos selecionados de ceratocone grau 2.

Metastasis in choroidal melanoma is frequent on advanced diseases, involving mainly the liver, lungs and central nervous system. We report a case of cutaneous metastasis in choroidal melanoma because is an unusual condition, even in advanced disease.

A ocorrência de metástases do melanoma de coróide é frequente na doença avançada, acometendo principalmente fígado, pulmões e sistema nervoso central. Relatamos um caso de melanoma de coróide com metástases cutâneas, por se tratar de acometimento raro, mesmo em casos avançados da doença.

Racemose Haemangioma (RH) is a congenital anomaly, characterized by retinal arteriovenous(AV) malformation. About 30% of patients have signs of central nervous system (CNS) involvement, which has been called the Wyburn-Mason syndrome. The authors present a 39-year-old male patient, who was admitted at the emergency room with decreased visual acuity of his left eye, for the last 6 days. Ophthalmic examination was performed and showed a visual acuity of 4/10 in his right eye and of 2/10 in the left eye. […]

The authors conducted a review of classical and conflicting theories of accommodation and presbyopia. They make a critical comparison with the findings of magnetic resonance imaging (MRI) that have been developed in recent decades. Based on these studies, formulates a new approach on the subject, shifting the focus of the discussion of the lens to the posterior pole of the eye.

Os autores revisaram as teorias clássicas e conflitantes sobre acomodação e presbiopia. E as compararam criticamente com os achados de imagem por ressonância magnética (MRI) que têm se desenvolvido nas últimas décadas. Baseado nestes estudos, formulam uma nova abordagem sobre o tema, mudando o foco da discussão do cristalino para o polo posterior do olho.