Abstract Currently, the amniotic membrane (AM) has obtained importance due to its ability to reduce inflammation, helping in the healing and epithelialization processes, having antimicrobial and antiviral properties and low immunogenicity. Its indications in ophthalmology have increased considerably in the past two decades. Objective: To describe the basic structure and biological properties of the AM, the components of the extracellular matrix and growth factors, the consequences of different techniques used in its preservation, and sterilization methods for the epithelium removal. […]

Graft-versus-host Disease (GVHD) is a major complication with high morbidity and mortality rates on patients undergoing hematopoietic stem cell transplantation. The ocular involvement, named ocular GVHD, may affect all structures of the eyes, but the lacrimal unit (lacrimal glands and ocular surface) is the main target of the inflammatory response mediated by the donor T cells. The development of dry eye disease is the main clinical ocular manifestation, and the association of a variety of therapeutics options is necessary. The […]

Conjunctival cysts in anophthalmic socket may have functional and aesthetic implications for the patients.Among the available treatment options, the use of trichloroacetic acid is relatively recent. Our reported cases showed a good outcome after 30 days of treatment, that was well tolerated by patients, with greater conjunctival tissue preservation.

OBJECTIVE: During the last years amniotic membrane (AM) autograft has been frequently used for reconstruction of the ocular surface in many diseases. This study intends to analyze the major indications for AM as well the results of this procedure. METHODS: Data of 107 patients who had done AM autograft surgery were retrospectively analised regarding the indications and postoperatory follow-up. RESULTS: The indications for AM autograft was ptherygium 33.64% (n=36), persistent epithelial defect 29.90% (n=32), simblepharum 18.69% (n=20), chemical injury 6.54%(n=7), […]