ABSTRACT Stiff-Person syndrome is a rare neuro-immunological condition predominantly affecting proximal and axial limb muscles, with a higher incidence in females aged between the third and seventh decades of life. Ophthalmological involvement is a significant aspect, often correlated with cerebellar dysfunction and various nystagmus forms. A 53 year-old female with a history of hypothyroidism and rectal polypectomy, presenting with diplopia, dizziness, and postural instability, eventually diagnosed with Stiff-Person syndrome. Treatment involves medications like diazepam and gabapentin, besides intravenous immunoglobulin therapy […]

ABSTRACT We present a case of an autosomal dominant optic neuropathy, known as Kjer’s disease. The condition can manifest since childhood, presenting with bilateral symmetric optic atrophy and progressive vision loss. Genetics play a crucial role in the differential diagnosis, due to the association with the OPA-1 gene. In this report, we describe the case of a young vegan woman, initially diagnosed with optic neuropathy due to nutritional deficiency, but with laboratory tests within normal limits and a significant family […]

ABSTRACT We describe a case of Irvine-Gass syndrome and the clinical decompensation of glaucoma after uneventful cataract surgery with resistance to conventional clinical treatment. Drainage tube implantation and intravitreal injection of dexamethasone were performed simultaneously with the resolution of cystoid macular edema and good control of intraocular pressure, which remained consistent after 1 year of follow-up.

ABSTRACT Retinal vasoproliferative tumor is a rare disease associated with several sight-threatening complications. The optimum management of retinal vasoproliferative tumor is unknown and the need of surgery arises when there is diagnostic uncertainty or sight-threatening complications, such as 23G pars plana vitrectomy, perfluorooctane retinal flattening, fluid drainage through a peripheral retinotomy, fluid-air exchange, laser photocoagulation of the retinal vasoproliferative tumor, and 12.5% C3F8 tamponade. We described two cases of retinal vasoproliferative tumor with exudative retinal detachment threatening the macula, treated […]

ABSTRACT Our objective was to report the case of the use of Xen® Gel Stent in the surgical treatment of glaucoma secondary to iridocorneal endothelial syndrome. Female patient, 38 years old, with unilateral glaucoma secondary to iridocorneal endothelial syndrome in the right eye, using maximum tolerable medications (three medications), with medicated intraocular pressure oscillating between 16 and 18 mmHg, demonstrating structural and functional progression, underwent minimally invasive bleb surgery with ab interno closed-conjunctival implantation of a Xen® Gel Stent. The […]

ABSTRACT The aim of this case report was to evaluate the outcome and methodology of a novel technique for conjunctival pigmentation using modified micropuncture to enhance the appearance of an ocular graft from an eviscerated eye. This approach used modified micropuncture for conjunctival pigmentation and sclera in an ocular graft. Due to the lack of a cornea, multiple sessions were required to ensure proper pigment penetration. The procedure’s effectiveness was evaluated based on aesthetic results and patient satisfaction. The technique […]

ABSTRACT Congenital stationary night blindness encompasses a heterogeneous group of inherited retinal dystrophies characterized by impaired scotopic vision from birth. This article provides a comprehensive overview of congenital stationary night blindness, focusing on its genetic underpinnings, clinical manifestations, and diagnostic approaches, with a specific emphasis on variants in the CACNA1F gene. Through a detailed case report of a 49-year-old male with congenital stationary night blindness attributed to a hemizygous variant in CACNA1F, we illustrate typical clinical presentations and correlate them […]

ABSTRACT This case report presents a patient who underwent photorefractive keratectomy 13 years after Acanthamoeba infection. The patient experienced prolonged difficulties in epithelialization during the postoperative period, leading to suspicion of reactivation. This case underscores the complexity and challenges in managing patients with a history of photorefractive keratectomy and ocular infections, particularly in cases involving Acanthamoeba. Understanding such cases is crucial for optimizing treatment strategies and achieving favorable outcomes.