ABSTRACT Objective: Embryonic exposure to valproic acid is a widely used model for the study of neurodevelopmental disorders such as autism spectrum disorders. In zebrafish, early exposure to valproic acid results in the major behavioral, neurological, and genetic phenotypes of this disorder. Autism spectrum disorders have several associated symptoms, such as changes in sensory processing, sleep problems, and hyper- or hyposensitivity to light. This work investigates the hypothesis of changes at the retinal level due to embryonic exposure to valproic […]

ABSTRACT Dead bag syndrome is one of the recently described causes of late intraocular lens dislocation. Its etiology is not yet fully understood, but it is related to the reduction or disappearance of lens epithelial cells with subsequent disaggregation of the capsular tissue. This study describes a case of late intraocular lens dislocation with confirmed disappearance of lens epithelial cells through histopathology. The contralateral eye appears to show clinical features consistent with dead bag syndrome. The eye affected by intraocular […]

Vivemos um momento de inflexão na medicina contemporânea, uma era em que a Inteligência Artificial (IA) promete redefinir os contornos do diagnóstico, da conduta e da própria relação médico-paciente. Porém, como advertia Freud, todo progresso técnico vem acompanhado de perdas simbólicas e novos desconfortos.() Nietzsche, por sua vez, alertava-nos contra os perigos da automatização do pensamento, da ilusão de um saber infalível que desconsidera a experiência humana.() A oftalmologia, especialidade profundamente visual, encontra-se no centro desse debate. A aplicação da […]

ABSTRACT Children with Shaken Baby Syndrome (SBS) often present with multi-layered retinal hemorrhages, with risks of retinal detachment, macular retinoschisis, and vitreous hemorrhages, depending on the impact of the head trauma. Permanent damage to vision can result from direct injury to the eyes or brain, the latter being the main cause of visual impairment. Retinal scarring and optic nerve atrophy are usually irreversible and can appear months after the injury. Ophthalmological findings can provide meaningful diagnostic data to the multidisciplinary […]

ABSTRACT Objective: To assess the Brazilian population’s knowledge and habits regarding glaucoma. Methods: A cross-sectional study was conducted with a random sample calculated to be representative of the Brazilian population. Data collection was conducted by a company specialized in population surveys through telephone calls. A structured questionnaire was used with questions about glaucoma, including its concept, risk factors, and treatment, as well as eye health prevention habits and attitudes. All interviews were recorded and reviewed. Results: The study population consisted […]

ABSTRACT Objective: To assess medication-related costs in patients with open-angle glaucoma subjected to iStent inject®. Methods: Retrospective study of patients with early-stage open-angle glaucoma who underwent iStent inject® implantation within the Brazilian private healthcare system and were followed for a period of 1 to 5 years. The study population comprised 234 patients with a mean age of 68.4 years old. The capacity to reduce intraocular pressure, amount of antiglaucoma medications required, and monthly cost of the necessary antiglaucoma medications during […]

ABSTRACT Duane Syndrome (DS) is a rare ocular disorder that causes congenital strabismus. It results from a failure of the abducens nerve (VI cranial nerve) to innervate the lateral rectus muscle, in addition to anomalous innervation of this muscle by the oculomotor nerve (III cranial nerve). The syndrome is characterized by restricted movements of adduction and abduction, narrowing of the palpebral fissure, abnormal ocular movements, and globe retraction. It affects about 0.1% of the population and accounts for 1-4% of […]

ABSTRACT Objective: to offer basic ophthalmological knowledge to the local community through a scientific exhibition and evaluate the impact on visitors’ learning. Methods: to hold an interactive exhibition on the human eye and ocular health at the Central Library (BCE) of the State University of Maringá (UEM-PR) in June and July 2024, open to the population. A 10-question questionnaire was administered before and after the students’ interaction with visitors at the exhibition. Results: 2,348 valid questionnaires were administered (1,174 initially […]